کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5213179 1383148 2016 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Synthesis of quaternary α-benzyl- and α-allyl-α-methylamino cyclobutanones
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Synthesis of quaternary α-benzyl- and α-allyl-α-methylamino cyclobutanones
چکیده انگلیسی

A simple and practical protocol for the construction of synthetically important quaternary α-benzyl- and α-allyl-α-methylamino cyclobutanones in good to high yield, via a sequential one-pot methylation/sigmatropic rearrangement, has been accomplished for the first time. The quaternary α-alkyl-α-amino cyclobutanones could be further manipulated, affording synthetically interesting scaffolds such as highly substituted tryptamines and cyclobuta-fused indolines.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron - Volume 72, Issue 50, 15 December 2016, Pages 8201-8209
نویسندگان
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