کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5214162 | 1383187 | 2016 | 11 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
A mild method for the replacement of a hydroxyl group by halogen. 1. Scope and chemoselectivity
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
α-Chloro-, bromo- and iodoenamines, which are readily prepared from the corresponding isobutyramides have been found to be excellent reagents for the transformation of a wide variety of alcohols or carboxylic acids into the corresponding halides. Yields are high and conditions are very mild thus allowing for the presence of sensitive functional groups. The reagents can be easily tuned allowing therefore the selective monohalogenation of polyhydroxylated molecules. The scope and chemoselectivity of the reactions have been studied and reaction mechanisms have been proposed.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron - Volume 72, Issue 3, 21 January 2016, Pages 420-430
Journal: Tetrahedron - Volume 72, Issue 3, 21 January 2016, Pages 420-430
نویسندگان
François Munyemana, Isabelle George, Alain Devos, Alain Colens, Eduard Badarau, Anne-Marie Frisque-Hesbain, Aurore Loudet, Edmond Differding, Jean-Marie Damien, Jeanine Rémion, Jacqueline Van Uytbergen, Léon Ghosez,