Bioxanthracenes and monomeric analogues from insect pathogenic fungus Conoideocrella luteorostrata Zimm. BCC 31648

Thirteen bioxanthracenes, including eight new 1-8, together with twelve oxanthracenes and analogues, including nine new 9-17, and two naturally occurring 18 and 19, were isolated from insect pathogenic fungus, Conoideocrella luteorostrata Zimm. BCC 31648. Structures were determined by NMR spectroscopic and MS spectrometric analyses. Compounds 14, 17, and 18 displayed antimalarial and cytotoxic activities while compounds 2, 9, 11, 12, 15 and 19 exhibited only cytotoxic activity.