کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5215691 1383240 2014 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
4,5-Dicyanoimidazole-promoted synthesis of dinucleoside polyphosphates and their analogs
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
4,5-Dicyanoimidazole-promoted synthesis of dinucleoside polyphosphates and their analogs
چکیده انگلیسی

A general and efficient P(V)-N activation method for the preparation of symmetrical and asymmetrical dinucleoside polyphosphates (NpnN′s, n=2-4) and P2,P3-CX2-dinucleoside tetraphosphates (X=H, F, and Cl) has been established. Twenty-two dinucleoside polyphosphates and their phosphonate analogs were synthesized from nucleoside 5′-phosphoropiperidates with 4,5-dicyanoimidazole as the activator in good to high yields.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron - Volume 70, Issue 30, 29 July 2014, Pages 4500-4506
نویسندگان
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