کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5216951 1383281 2014 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
New tetracyclic 1,4-oxazepines constructed via practically simple tandem condensation strategy from readily available synthons
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
New tetracyclic 1,4-oxazepines constructed via practically simple tandem condensation strategy from readily available synthons
چکیده انگلیسی

A streamlined synthetic methodology towards novel tetracyclic 1,4-oxazepines from readily available precursors is described. The compounds, designed as more soluble version of the earlier described, poorly soluble dibenzo[b,f][1,4]oxazepines, were obtained in high yields and as a single regioisomer as a result of three tandem chemical events—nucleophilic aromatic substitution, Smiles rearrangement and denitrocyclization.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron - Volume 70, Issue 5, 4 February 2014, Pages 1077–1083