کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5217372 1383293 2013 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Cobalt-catalyzed ortho-alkenylation of aromatic aldimines via chelation-assisted C-H bond activation
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Cobalt-catalyzed ortho-alkenylation of aromatic aldimines via chelation-assisted C-H bond activation
چکیده انگلیسی

An ortho-alkenylation reaction of an aromatic aldimine with an internal alkyne is efficiently promoted by a cobalt catalyst generated from CoBr2, triarylphosphine, and iPrMgBr. The reaction takes place under mild room-temperature conditions to afford, upon acidic hydrolysis, a variety of ortho-alkenylated aromatic aldehydes in moderate to excellent yields. The neighboring formyl and alkenyl groups in the product can be utilized as synthetic handles for the facile construction of indene and naphthalene carbocycles.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron - Volume 69, Issue 22, 3 June 2013, Pages 4459-4465
نویسندگان
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