کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5217481 1383297 2013 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Total synthesis of masked Alternaria mycotoxins-sulfates and glucosides of alternariol (AOH) and alternariol-9-methyl ether (AME)
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Total synthesis of masked Alternaria mycotoxins-sulfates and glucosides of alternariol (AOH) and alternariol-9-methyl ether (AME)
چکیده انگلیسی

The synthesis of different protected alternariol derivatives using intramolecular cyclization of iodoresorcylic acid phenyl esters by palladium-catalyzed C-H activation as key step is presented. Furthermore, chemical sulfation and glucosylation were applied for the preparation of conjugated Alternaria mycotoxins. These compounds are suspected to be formed during metabolism in contaminated plants. Therefore, all synthetic conjugates prepared within this work serve as reference materials for further studies in the fields of bioanalytics and toxicology of mycotoxins.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron - Volume 69, Issue 48, 2 December 2013, Pages 10322-10330
نویسندگان
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