کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5217620 1383301 2014 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Bioactive polyketides from the fungus Astrocystis sp. BCC 22166
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Bioactive polyketides from the fungus Astrocystis sp. BCC 22166
چکیده انگلیسی

Five new compounds, phthalide 1, dihydroisocoumarin 2, and 3, pyrone 4, and benzophenone 5, together with nine known compounds, 3,4-dihydro-4,5,8-trihydroxy-3-methylisocoumarin, sclerotinin A, methyl-8-hydroxy-6-methylxanthone-1-carboxylate, sydowinin A, conioxanthone A, 1,3,8-trihydroxy-6-methylxanthone, 1,8-dihydroxy-3-methoxy-6-methylxanthone, coniochaetone B, and xylaranol B, were isolated from the fungus Astrocystis sp. BCC 22166. Structures of these compounds were elucidated using NMR spectroscopic and MS spectrometric analyses. Compound 1 exhibited antibacterial activity against Bacillus cereus (IC50=12.5 μg/mL) while compound 2 showed cytotoxicity to KB and Vero cells (IC50=22.6 and 48.2 μg/mL).

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron - Volume 70, Issue 12, 25 March 2014, Pages 2129-2133
نویسندگان
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