کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5217794 | 1383306 | 2014 | 9 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Solvent-free Brønsted acid catalysed alkylation of arenes and heteroarenes with benzylic alcohols Solvent-free Brønsted acid catalysed alkylation of arenes and heteroarenes with benzylic alcohols](/preview/png/5217794.png)
A simple and efficient alkylation of aromatic and heteroaromatic compounds via the direct SN1-type nucleophilic substitution of benzylic alcohols in the presence of catalytic amounts of the strong Brønsted acid o-benzenedisulfonimide under neat conditions is herein reported. A library of di- and triaryl (and heteroaryl) methanes was prepared in good yields and high regioselectivity. The observed reactivity was shown to be in agreement with Mayr's nucleophilicity and electrophilicity scales.
232A library of di- and triaryl (and heteroaryl) methanes was prepared in good yields and regioselectivity via a simple and efficient alkylation of aromatic compounds through direct SN1-type alcohol nucleophilic substitution in the presence of o-benzenedisulfonimide under neat conditions.
Journal: Tetrahedron - Volume 70, Issue 9, 4 March 2014, Pages 1818-1826