کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5218318 | 1383323 | 2013 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Diversity oriented catalyst-free and solvent-free one-pot MCR at room temperature: rapid and regioselective convergent approach to highly functionalized dihydro-4H-thiopyrans
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موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Highly convergent and regioselective approach to hitherto unreported and synthetically demanding 6-cycloamino-2-(methyl/benzyl)sulfanyl-3-(aroyl/hetaroyl/alkanoyl)-4-aryl-5,6-dihydro-4H-thiopyrans has been developed via one-pot three-component domino coupling of β-oxodithioesters, α,β-unsaturated aldehydes, and cyclic aliphatic secondary amines at room temperature under catalyst-free and solvent-free conditions. The attractive features of this strategy include mild conditions, short reaction time, high atom-economy, excellent yields, and efficacy of forming three new bonds (C–C, C–N and C–S) and one ring in a single stroke.
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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron - Volume 69, Issue 37, 16 September 2013, Pages 8013–8018
Journal: Tetrahedron - Volume 69, Issue 37, 16 September 2013, Pages 8013–8018