کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5218777 1383337 2013 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
MCM-41-immobilized bidentate nitrogen copper(I) complex: a highly efficient and recyclable catalyst for Buchwald N-arylation of indoles
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
MCM-41-immobilized bidentate nitrogen copper(I) complex: a highly efficient and recyclable catalyst for Buchwald N-arylation of indoles
چکیده انگلیسی

The heterogeneous N-arylation reaction of indoles with aryl halides was achieved in toluene at 110 °C by using 4 mol % MCM-41-immobilized bidentate nitrogen copper(I) complex [MCM-41-2N-CuI] as catalyst and K3PO4 as base, yielding a variety of N-arylindoles in good to excellent yields. The heterogeneous copper catalyst exhibited as high activity as homogeneous CuI/diamine catalytic system and can be easily prepared by a simple two-step procedure from commercially available and cheap reagents and recovered by a simple filtration of the reaction solution and reused for 10 cycles with almost consistent activity.

An environmentally friendly, efficient, and practical method for the synthesis of N-arylindoles has been developed by an MCM-41-immobilized bidentate nitrogen copper complex-catalyzed N-arylation reaction of indoles with aryl halides under mild reaction conditions.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron - Volume 69, Issue 26, 1 July 2013, Pages 5444-5450
نویسندگان
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