کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5218891 | 1383341 | 2013 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Synthesis of novel nucleosides and stereoselectivity of N-glycosidation
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Synthesis of novel nucleosides and stereoselectivity of N-glycosidation Synthesis of novel nucleosides and stereoselectivity of N-glycosidation](/preview/png/5218891.png)
چکیده انگلیسی
An efficient synthetic route for novel nucleosides has been realized. We report the formation of α-isomers in spite of neighboring group participation by the benzoyl group at the 2-position in N-glycosidation as well as discuss the stereoselectivity observed. We also found that non-silylated pyrimidin-2(1H)-ones and pyrimidin-2(1H)-thiones having aromatic structures reacted with 1-fluororibose in the presence of a Lewis acid to give the corresponding nucleosides in good to high yield.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron - Volume 69, Issue 2, 14 January 2013, Pages 595-599
Journal: Tetrahedron - Volume 69, Issue 2, 14 January 2013, Pages 595-599
نویسندگان
Kyosuke Michigami, Satoshi Uchida, Miho Adachi, Masahiko Hayashi,