کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5219668 1383364 2012 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Rhodium catalyzed synthesis of isoindolinones via C-H activation of N-benzoylsulfonamides
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Rhodium catalyzed synthesis of isoindolinones via C-H activation of N-benzoylsulfonamides
چکیده انگلیسی

An efficient approach to a wide range of isoindolinones, including 3-monosubstituted and 3,3-disubstituted isoindolinones, from the annulation of N-benzoylsulfonamides with olefins and diazoacetate has been developed. The transformation is broadly compatible with both terminal and internal olefins. Moreover, diazoacetate is for the first time incorporated into an amide-directed C-H functionalization reaction. Specifically, the rhodium complex [{RhCl2Cp*}2] enables the in situ dimerization of diazoacetate in addition to its role in catalyzing C-H functionalization/cross-coupling.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron - Volume 68, Issue 45, 11 November 2012, Pages 9192-9199
نویسندگان
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