Skeletal diversity via Pd(0) catalysed three-component cascades of allene and halides or triflates with protected hydroxylamines and formamide

The reactions of allene gas (1 atm) and of 1,1-dimethylallene with a range protected hydroxylamines and formamide with aryl/heteroaryl iodides, bromides and triflates under Pd(0) catalysis lead to a skeletally diverse range of products in good yield. The cascades tolerate both electron withdrawing and electron donating substrates and 1,1-dimethylallene reacts regioselectively in all cases.