Piecing together the puzzle: understanding a mild, metal free reduction method for the large scale synthesis of hydrazines

A key intermediate for the synthesis of hydrazines via a mild, metal free reduction of diazonium salts has been isolated and characterized by X-ray analysis. The presence of this intermediate is general, as demonstrated by the preparation of a number of analogues. A discussion of the mechanism and potential benefits of such a process are also described.

Figure optionsDownload as PowerPoint slide