Chemistry of imidazo[2,1-b][1,3,4]thiadiazoles

Research work on Imidazo[2,1-b][1,3,4]thiadiazole ring system extending over a period of 55 years led to some drug candidates and promising lead molecules. This review summarizes the synthetic methodologies, chemical reactions, crystal structure studies, synthetic and pharmacological utility of these compounds. The review contains over 180 references.