کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5220550 1383391 2011 12 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Spiro-sulfamidate and sulfate nucleosides via 2′ and 3′-C-branched-chain sugars and nucleosides
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Spiro-sulfamidate and sulfate nucleosides via 2′ and 3′-C-branched-chain sugars and nucleosides
چکیده انگلیسی

C-branched-chain sugars and nucleosides were obtained by organocatalysis from ulose derivatives. After a reduction step, the corresponding 1,3-diol was derivatized into 3′-spiro-sulfamidates and unexpected sulfates by treatment with a Burgess reagent. Deprotection of the Boc-derivatives was carried out while preserving the cyclic sulfate. An example of ring opening of the cyclic sulfate derivative with sodium azide leading to the corresponding 3′-C-azidoalkyl branched-chain nucleosides is given.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron - Volume 67, Issue 33, 19 August 2011, Pages 6006-6017
نویسندگان
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