DABCO-catalyzed C-C bond formation reaction between electron-deficient alkynes and 1,3-dicarbonyl compounds

An excellent catalyst DABCO has been found to catalyze C-C bond formation reaction between activated methylenes and alkynes. The transformation has provided a facile route for the synthesis of 2H-pyran-2-ones or unsaturated alkenoic acid ester derivatives and explored the new possibilities of N-catalysts for Michael addition of nucleophiles with alkynoates.

A novel DABCO-catalyzed addition of 1,3-dicarbonyl compounds to alkynes has been developed for the formation of C-C bonds. The transformation has provided a facile route for the synthesis of 2H-pyran-2-ones or unsaturated alkenoic acid ester derivatives and explored the new possibilities of N-catalysts for Michael addition of nucleophiles with alkynoates.