کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5220765 | 1383398 | 2011 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Sporolide B: synthetic studies
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موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Studies directed toward the synthesis of the architecturally complex marine natural product sporolide BÂ are described. Synthetic analysis suggested advanced hydroquinone and benzodiquinane fragments, which upon elaboration were successfully united via an ester linkage. Macrocyclization studies were then carried out, and although a novel macrocyclization product was obtained, subsequent studies revealed that the tertiary hydroxyls at C(6) and C(10) were too sterically encumbered to participate in a successful macrocyclization to furnish sporolide B.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron - Volume 67, Issue 35, 2 September 2011, Pages 6697-6706
Journal: Tetrahedron - Volume 67, Issue 35, 2 September 2011, Pages 6697-6706
نویسندگان
Jeffery A. Gladding, James P. Bacci, Scott A. Shaw, Amos B. III,