Reactivity of sugar α-aminonitrile derivatives under titanium-mediated cyclopropanation conditions

The reactivity of different sugar α-aminonitriles has been studied under titanium-mediated cyclopropanation conditions. This study has been performed on amide, lactam, and imide derivatives. It has been possible to obtain spiro[furanose-3,3′-(3′,5′,6′,7′-tetrahydrospiro[cyclopropane-1,2′-pyrrolo[1,2-a]imidazole])] derivatives.