کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5221474 | 1383421 | 2010 | 12 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Preparation and biological evaluation of key fragments and open analogs of scleritodermin A
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موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
The synthesis of key fragments of scleritodermin A, their assembly, and their biological evaluation as cytotoxic and anthelmintic were performed. Highlights of the synthetic route include formation of the α-ketoamide linkage and use of stereocontrolled reactions. Open analogs of this natural product were obtained using a convergent strategy.
The synthesis of different key fragments of scleritodermin A, their assembly to obtain open analogs, and biological evaluation of the obtained products as cytotoxic and anthelmintic were performed.Figure optionsDownload as PowerPoint slide
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron - Volume 66, Issue 29, 17 July 2010, Pages 5384–5395
Journal: Tetrahedron - Volume 66, Issue 29, 17 July 2010, Pages 5384–5395