کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5221720 | 1383430 | 2011 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
A one-pot synthesis of substituted pyrido[2,3-b]indolizines
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: A one-pot synthesis of substituted pyrido[2,3-b]indolizines A one-pot synthesis of substituted pyrido[2,3-b]indolizines](/preview/png/5221720.png)
چکیده انگلیسی
An efficient and novel approach to the synthesis of substituted pyrido[2,3-b]indolizine-10-carbonitriles was developed. These structures are practically unavailable through previously described methods. The cascade transformation involves the reaction of α,β-unsaturated carbonyl compounds with a stable dimer prepared from 1-(cyanomethyl)pyridinium chloride. The reaction was performed under reflux conditions in ethanol/water and in the presence of sodium acetate. This procedure represents a eco-friendly regioselective approach to the pyrido[2,3-b]indolizine core structure.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron - Volume 67, Issue 6, 11 February 2011, Pages 1071-1075
Journal: Tetrahedron - Volume 67, Issue 6, 11 February 2011, Pages 1071-1075
نویسندگان
Fernanda Proença, Marta Costa,