کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5221832 | 1383433 | 2011 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Highly regio- and diastereoselective halohydroxylation of olefins: a facile synthesis of vicinal halohydrins
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Highly regio- and diastereoselective halohydroxylation of olefins: a facile synthesis of vicinal halohydrins Highly regio- and diastereoselective halohydroxylation of olefins: a facile synthesis of vicinal halohydrins](/preview/png/5221832.png)
چکیده انگلیسی
An efficient method for the synthesis of vicinal chlorohydrin or bromohydrin derivatives has been developed on the basis of direct halohydroxylation of various olefins with electrondonating or withdrawing substituent. The reactions were carried out under mild conditions in the presence of N-tosyl-l-threonine (NTsLT) as an acidic additive using chloramine T trihydrate, 1,3-dichloro-5,5-dimethylhydantoin (DCDMH) or N-bromoacetamide (AcNHBr) as the halogen source, respectively, affording the corresponding vicinal halohydrins in good to high yields with excellent regio- and stereoselectivities.
Direct halohydroxylation of olefins provided a facile synthesis of vic-halohydrins in excellent yield with high chemo-, regio- and stereoselectivity.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron - Volume 67, Issue 36, 9 September 2011, Pages 6859-6867
Journal: Tetrahedron - Volume 67, Issue 36, 9 September 2011, Pages 6859-6867
نویسندگان
Jinglei Zhang, Jie Wang, Zhuibai Qiu, Yang Wang,