Normal electron demand Diels–Alder cycloaddition of indoles to 2,3-dimethyl-1,3-butadiene

The influence of experimental conditions and of a wide range of electron-withdrawing indole substituents has been studied in the thermally activated and Lewis acid activated intermolecular Diels–Alder cycloaddition of electron-poor indoles to 2,3-dimethyl-1,3-butadiene.

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