کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5222518 1383457 2011 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A novel multicomponent approach to the synthesis of 1,3-thiazolidine-2-thiones
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
A novel multicomponent approach to the synthesis of 1,3-thiazolidine-2-thiones
چکیده انگلیسی

An easy, efficient, and simple one-pot approach for the synthesis of 1,3-thiazolidine-2-thiones via multicomponent reaction is reported. The reaction of a primary amine with carbon disulfide in the presence of dibenzoylacetylene or bis(4-methyl-1-benzoyl)acetylene in a mixture of CH2Cl2 and H2O after 5 h, afforded the title compound as alkene diastereomers.

A facile and direct synthetic entry to 1,3-thiazolidine-2-thione derivatives is reported which involves the three-component coupling of carbon disulfide, primary amines and dibenzoylacetylene or bis(4-methyl-1-benzoyl)acetylene under neutral conditions in a mixture of CH2Cl2 and H2O.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron - Volume 67, Issue 9, 4 March 2011, Pages 1709-1715
نویسندگان
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