Alkynyl-2-deoxy-d-riboses, a cornucopia for the generation of families of C-nucleosides

This study focuses on the preparation of some 1-alkynyl-2-deoxy-d-riboses and their application to the generation of C-nucleosides analogues. Examples are provided in which the alkyne functionality took part in alkylation or cycloaddition reactions. A discussion of the protecting group used is provided.