کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5223007 | 1383474 | 2011 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Highly enantioselective synthesis of α-fluoro-α-nitro esters via organocatalyzed asymmetric Michael addition
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Highly enantioselective synthesis of α-fluoro-α-nitro esters via organocatalyzed asymmetric Michael addition Highly enantioselective synthesis of α-fluoro-α-nitro esters via organocatalyzed asymmetric Michael addition](/preview/png/5223007.png)
چکیده انگلیسی
Primary amines catalyzed the asymmetric Michael addition of ethyl 2-fluoro-2-nitroacetate to enones to provide chiral α-fluoro-α-nitro ester ketones with two contiguous stereogenic centers, one of which is a fluorinated quaternary chiral center, with excellent enantioselectivities and in moderate to good yields.
Primary amines perform as efficient organocatalysts for the asymmetric addition of α-fluorinated nitroacetate to enones, giving the Michael adducts with two contiguous stereogenic centers, one of which is a fluorinated quaternary chiral center in good to excellent yields and enantioselectivities.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron - Volume 67, Issue 2, 14 January 2011, Pages 312-317
Journal: Tetrahedron - Volume 67, Issue 2, 14 January 2011, Pages 312-317
نویسندگان
Hai-Feng Cui, Peng Li, Xiao-Wei Wang, Zhuo Chai, Ying-Quan Yang, Yue-Peng Cai, Shi-Zheng Zhu, Gang Zhao,