Diastereoselective Michael addition of 2H-2-oxo-1,4,2-oxaza phosphinanes to olefins

Diastereoselective Michael additions of 2-hydrogeno-2-oxo-1,4,2-oxazaphosphinanes to olefins were described. Phosphinopeptide compounds were obtained in very good yield (up to 90%) and diasteromeric excesses ranging from 26 to 78%.

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