CuI/La(OTf)3 catalyzed, one-pot synthesis of isomeric ellipticine derivatives in ionic liquid

An efficient method for one-pot synthesis of isomeric ellipticine derivatives through CuI/La(OTf)3 catalyzed sequential inter/intramolecular cyclization of substituted alkynes with imines followed by aromatization is reported in good to excellent yields.

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