کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5225226 1383541 2007 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Total synthesis of cyercene A and the biomimetic synthesis of (±)-9,10-deoxytridachione and (±)-ocellapyrone A
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Total synthesis of cyercene A and the biomimetic synthesis of (±)-9,10-deoxytridachione and (±)-ocellapyrone A
چکیده انگلیسی

This paper summarises our detailed study towards the biomimetic synthesis of the complex polypropionate derived natural product (±)-9,10-deoxytridachione. A previous study based on the elaboration of functionalised γ-pyrones allowed us to synthesise cyercene A. The same efficient methodology has been applied for the elaboration of a more complex fully conjugated γ-pyrone polyene. Our approach centred on a key tandem Suzuki-coupling/electrocyclisation reaction, which supports a possible biosynthetic pathway for this class of natural products. A related compound was obtained during our studies, which we identified as the correct structure of ocellapyrone A.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron - Volume 63, Issue 21, 21 May 2007, Pages 4500-4509
نویسندگان
, , , , , ,