BF3–OEt2-mediated rearrangement of 4-substituted-5,5-diphenylazepan-4-ols

Synthesis of 2-(2-substituted-ethylidene)-3,3-diphenylpyrrolidines has been established starting from different 4-substituted-4-aryl-5,5-diphenylazepan-4-ols via boron trifluoride etherate-mediated rearrangement.

Figure optionsDownload as PowerPoint slide