کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5225550 1383550 2007 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Preparation of functionalized 3,4-pyridynes via 2-magnesiated diaryl sulfonates
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Preparation of functionalized 3,4-pyridynes via 2-magnesiated diaryl sulfonates
چکیده انگلیسی

The preparation of functionalized 3,4-pyridynes of type 1 as highly reactive intermediates has been achieved by the controlled elimination of readily generated 2-magnesiated diaryl sulfonates of type 2 obtained by a low temperature I/Mg- or Br/Mg-exchange starting from the corresponding halides of type 3. After trapping with furan, moderate to good yields of the desired functionalized cycloadducts of type 4 are obtained. The addition of a magnesium arylthiolate or magnesium phenylselenide to 3,4-pyridyne followed by quenching with an electrophile is also described.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron - Volume 63, Issue 13, 26 March 2007, Pages 2787-2797
نویسندگان
, , ,