PEG (300)-PdCl2 promoted efficient and convenient Suzuki-Miyaura coupling of aryl chlorides with arylboronic acids

PEG (300) was found as an effective medium for the PdCl2-catalyzed Suzuki-Miyaura cross-coupling of aryl chlorides with various phenylboronic acids. This cross-coupling pathway conveniently and efficiently gave good to excellent yields of corresponding biaryl nucleus under mild conditions.