Highly efficient reusable polymer-supported Pd catalysts of general use for the Suzuki reaction

Short and efficient syntheses of various polymer-supported Pd catalysts are reported. The reactivity of these catalysts has been determined for the Suzuki reaction. It turned out that the (tert-butylphenylphosphinomethyl)polystyrene-supported Pd catalyst 2′a is highly efficient for versatile Suzuki reactions from aryl chlorides. These couplings are performed in the presence of low amounts (4 mequiv) of supported Pd, the catalyst can be reused more than seven times without loss of efficiency and the Pd leaching is extremely low (<0.1% of the initial amount).