کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5226797 1383586 2006 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Reaction between glutaric anhydride and N-benzylidenebenzylamine, and further transformations to new substituted piperidin-2-ones
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Reaction between glutaric anhydride and N-benzylidenebenzylamine, and further transformations to new substituted piperidin-2-ones
چکیده انگلیسی

The reaction between glutaric anhydride (1) and N-benzylidenebenzylamine (3) was studied in detail by 1H NMR spectroscopy under different reaction conditions. The major product was (±)-trans-1-benzyl-6-oxo-2-phenylpiperidine-3-carboxylic acid (2), which was converted into new substituted piperidin-2-ones via transformations of the carboxylic group. The final products are expected to possess pharmaceutical activities, and the relevant screenings are in course.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron - Volume 62, Issue 35, 28 August 2006, Pages 8318-8326
نویسندگان
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