Synthesis of new 2-oxosparteine derivatives

For the first time, substituents to the 3-position of 2-oxosparteine have been introduced. The synthesis of 3-phenylthiolupanine, 3,3-di(phenylthio)lupanine, 3-dehydrolupanine, 3-bromodehydro-lupanine and 2-thiono-3-dehydrosparteine has been described. The stereochemistry of these compounds has been determined and by NMR spectroscopy and X-ray crystallography.

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