کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5227462 1383606 2008 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Chromium(II) chloride-promoted reductive β-elimination of 1,1-dihalo alditols. Synthesis of highly functionalized alk-1-enyl halides
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Chromium(II) chloride-promoted reductive β-elimination of 1,1-dihalo alditols. Synthesis of highly functionalized alk-1-enyl halides
چکیده انگلیسی

A new general synthetic route to obtain highly functionalized (Z)- and (E)-alk-1-enyl halides is described, where the halogen can be indistinctly F, Cl, Br, and I. The procedure involves CrCl2-promoted reductive elimination of β-O-substituted gem-dihalo alditols easily accessible from carbohydrates. The simplicity and mildness of the reaction conditions and their compatibility with different functional groups increase the synthetic potential of this methodology.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron - Volume 64, Issue 47, 17 November 2008, Pages 10706-10713
نویسندگان
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