کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5228100 1383624 2008 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Synthesis and photophysical characterization of new fluorescent bis-amino acids bearing a heterocyclic bridge containing benzoxazole and thiophene
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Synthesis and photophysical characterization of new fluorescent bis-amino acids bearing a heterocyclic bridge containing benzoxazole and thiophene
چکیده انگلیسی

A series of new bis-alanine derivatives bearing (oligo)thiophene and benzoxazole units as the heteroaromatic bridge were synthesized in moderate to good yields. The photophysical characterization of these bis-amino acids was performed by UV-vis absorption and fluorescence emission studies and revealed that the compounds displayed exceptionally high fluorescence quantum yields, making them good candidates for application as fluorescent probes when incorporated into peptides, as well as peptide conformation-restricting and cross-linking elements.

New highly fluorescent bis-amino acids based on alanine bearing (oligo)thiophene and benzoxazole units as the heterocyclic bridge were synthesized in moderate to good yields. Evaluation of the photophysical properties of the synthesized bis-amino acids revealed that they display exceptionally high fluorescence quantum yields, making them good candidates for application as fluorescent probes when incorporated into peptides, as well as peptide conformation-restricting and cross-linking elements.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron - Volume 64, Issue 41, 6 October 2008, Pages 9733-9737
نویسندگان
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