کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5228938 1383647 2008 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Benzylation of morphinandienes and new aspects of their acid-catalyzed rearrangement to new aporphines
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Benzylation of morphinandienes and new aspects of their acid-catalyzed rearrangement to new aporphines
چکیده انگلیسی

The benzylation of thebaine and 6-demethoxythebaine resulted in different product mixtures. Explanations were given for both the observed differences in the ratio of 5β- versus 7-benzyl products and the deviation of the electronic structure of ring C of 7-benzyl products. The acid-catalyzed rearrangement of morphinan-5,8-dienes, 5,6- and 6,7-disubstituted morphinan-6,8-dienes was achieved and mechanistic interpretations for the formation of new, potentially dopamine-active aporphines were provided.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron - Volume 64, Issue 25, 16 June 2008, Pages 5851-5860
نویسندگان
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