A facile approach to polysubstituted 2-pyridones. Application to the synthesis of 3,4-disubstituted isoquinolinone and total synthesis of oxyisoterihanine

We have disclosed an efficient and regiocontrolled synthesis of polysubstituted 2-pyridones, synthesis of 3,4-disubstituted isoquinolinone, and total synthesis of oxyisoterihanine.