کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5231135 | 1383716 | 2005 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
A convenient and efficient ring-opening reaction of aziridines with acetylenes and synthesis of dihydropyrroles
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: A convenient and efficient ring-opening reaction of aziridines with acetylenes and synthesis of dihydropyrroles A convenient and efficient ring-opening reaction of aziridines with acetylenes and synthesis of dihydropyrroles](/preview/png/5231135.png)
چکیده انگلیسی
In the presence of tBuOK, reaction of acetylenes with N-Ts substituted aziridines derived from both cyclic and acyclic alkenes at room temperature gave rise to homopropargylamines in good to high yields and in high regioselectivity. Not only Ph- and Me3Si-substituted acetylenes but also acetylene itself was suitable reagents. Treatment of ring-opening products with I2 and AgOAc in the presence of K2CO3 provided dihydropyrroles in high yields. One-pot synthesis of dihydropyrroles was also realized by the reaction of aziridines and phenylacetylene in the presence of NaH followed by the treatment with I2 and AgOAc.
Graphical Abstract
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron - Volume 61, Issue 40, 3 October 2005, Pages 9586-9593
Journal: Tetrahedron - Volume 61, Issue 40, 3 October 2005, Pages 9586-9593
نویسندگان
Chang-Hua Ding, Li-Xin Dai, Xue-Long Hou,