Amygdaloidins A-L, twelve new 13 α-OH jatrophane diterpenes from Euphorbia amygdaloides L.

Amygdaloidins A-L, new jatrophane diterpenes with unique substitution pattern, have been isolated and their structures established by NMR and MS methods. To deeper investigate the two main conformations adopted by the jatrophanes, we have carried out a molecular modeling calculation on amygdaloidin A and on the previously isolated euphodendroidin I.