Synthesis of a new class of keto-linked bis heterocycles

The 1,3-dipolar cycloaddition of tosyl methyl isocyanide, nitrile imines and nitrile oxides to 2-methyl-1-phenyl-5-aryl-1,4-pentadien-3-one (1) provides a simple, facile and elegant methodology to develop keto-linked bis heterocycles.