An intermolecular iodoamination of allenamides with sulfonamides mediated by N-iodosuccinimide

A new method was developed to synthesize iodine-substituted allylamino Z-enamides through N-iodosuccinimide-mediated intermolecular iodoamination of allenamides. These reactions proceed rapidly and tolerate a broad scope of substrates. The conjugated sulfimide ion species probably acts as the key intermediate.145