Alternative synthetic route to annulated diaminopyrimidines

- A one pot reaction was optimized to obtain annulated diaminopyrimidines.
- The complete reaction can be carried out in 30 min.
- The synthetic route is applicable to a large variety of cyanamides and dinitriles.
- The use of cyanamides confers a large versatility.
- The reaction can be applied to obtain quinazolone derivatives.