کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5262378 1385177 2014 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A facile method for synthesizing selenoglycosides based on selenium-transfer to glycosyl imidate
ترجمه فارسی عنوان
یک روش آسان برای سنتز سلنوگلیکوزید ها بر اساس انتقال سلنیوم به گلیکوزیل امیدات
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
چکیده انگلیسی
A facile reaction for constructing selenoglycosides has been developed based on the transacetalization reaction between a selenoacetal and a glycosyl imidate. Glycosyl imidates were activated with TMSOTf to produce oxocarbenium ion, which reacted with benzyloxymethyl alkyl (aryl) selenide, providing alky (or aryl) selenoglycosides in high yields. Furthermore, this reaction was utilized in the synthesis of 2-(trimethylsilyl)ethylselenoglycoside, which, upon treatment with TBAF in the presence of an electrophile, was transformed into other selenoglycosides.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron Letters - Volume 55, Issue 11, 12 March 2014, Pages 1920-1923
نویسندگان
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