کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5263974 1385239 2013 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Intermolecular sp3 C-H bond functionalization of alkyl alkanoates as a new method for the one-pot synthesis of functional neo alkyl alkanoates with remote functional groups
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Intermolecular sp3 C-H bond functionalization of alkyl alkanoates as a new method for the one-pot synthesis of functional neo alkyl alkanoates with remote functional groups
چکیده انگلیسی
The one-pot, regioselective, remote functionalization of alkyl alkanoates, [ROCOCnH2n+1 (R = Me, Et, n = 7-9)] via the Csp3-H bond cleavage with CO and various nucleophiles [iPrOH, CF3CH2OH, H(CF2)2CH2OH, HCCCH2OH, morpholine, diethylamine, furan, thiophene, and anisole] in the presence of the superelectrophilic complex, CBr4·2AlBr3 has been performed for the first time. This methodology provides access to new synthetically challenging and promising groups of derivatives of dicarboxylic acids possessing a neo-structure, such as esters and amides, and aromatic or heteroaromatic ketones containing an ester group.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron Letters - Volume 54, Issue 45, 6 November 2013, Pages 6037-6040
نویسندگان
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