کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5264377 | 1385252 | 2014 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
A convenient method for the Ru(0)-catalyzed regioselective deuteration of N-alkyl-substituted anilines
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موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: A convenient method for the Ru(0)-catalyzed regioselective deuteration of N-alkyl-substituted anilines A convenient method for the Ru(0)-catalyzed regioselective deuteration of N-alkyl-substituted anilines](/preview/png/5264377.png)
چکیده انگلیسی
A highly effective and operationally practical method for the regioselective deuteration of N-alkyl-substituted anilines employing Ru3(CO)12 (⩽1 mol %) as catalyst and D2O as deuterium source was described. A variety of N-alkyl-substituted anilines were efficiently deuterated (up to 98%) at the ortho and/or para position with respect to the nitrogen at neutral conditions. Under the present conditions, deuterated anilines can be easily obtained with simple extraction and evaporation. Substituents with aromatic methoxy groups would not influence the selectivity compared to previous method.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron Letters - Volume 55, Issue 36, 3 September 2014, Pages 5070-5073
Journal: Tetrahedron Letters - Volume 55, Issue 36, 3 September 2014, Pages 5070-5073
نویسندگان
Miao Zhan, Hongxia Jiang, Xuehai Pang, Tao Zhang, Ruixue Xu, Lifeng Zhao, Yu Liu, Yu Gong, Yuanwei Chen,