کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5265286 1385280 2013 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Catalyst controlled regioselective Suzuki cross-coupling of 2-(4-bromophenyl)-5-chloropyrazine
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Catalyst controlled regioselective Suzuki cross-coupling of 2-(4-bromophenyl)-5-chloropyrazine
چکیده انگلیسی
The Suzuki cross-coupling between 2-(4-bromophenyl)-5-chloropyrazine and a range of aryl boronic acids has been investigated. The regioselectivity of the reaction can be switched between the aryl bromide and pyrazinyl chloride positions by changing the ligand associated with the palladium catalyst. Xantphos has shown excellent selectivity for the pyrazinyl chloride, with most other ligands showing preferential selectivity for the aryl bromide.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron Letters - Volume 54, Issue 34, 21 August 2013, Pages 4529-4532
نویسندگان
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