کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5266308 | 1385307 | 2012 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
PEG grafted AM SURE⢠resin and its application to solid-phase peptide synthesis
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موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: PEG grafted AM SURE⢠resin and its application to solid-phase peptide synthesis PEG grafted AM SURE⢠resin and its application to solid-phase peptide synthesis](/preview/png/5266308.png)
چکیده انگلیسی
PEGylated core-shell type resin (PEG-AM SURE) was developed by modifying the surface of AM SURE⢠resin with diamino PEG. The conditions for the PEG coupling reaction were optimized by adjusting PEG chain cross-linking and the amount of free amino groups to ensure a enough loading level of functional groups on the resin (>0.30-0.39 mmol NH2/g). The resulting PEG-AM SURE resin showed better performance than conventional resins during solid-phase peptide synthesis of JR10-mer and β2m58-69 12-mer.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tetrahedron Letters - Volume 53, Issue 34, 22 August 2012, Pages 4576-4579
Journal: Tetrahedron Letters - Volume 53, Issue 34, 22 August 2012, Pages 4576-4579
نویسندگان
Mira Kim, Yong-Sun Park, Dong-Sik Shin, Song Lee, Yoon-Sik Lee,